Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury. Nina Colitti, Edwige Rice, ..., Nathalie Vergnolle, et al., Advanced Science 2026. DOI: 10.1002/advs.202503362

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review. Andreas Papapetropoulos, Stavros Topouzis, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70376

The role of dietary patterns on epigenetic and inflammatory aging based on the INSPIRE-T study. Natasha Grande de França, Yves Rolland, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., Communications Medicine 2026. DOI: 10.1038/s43856-026-01643-1

High thrombin activity associated with crohn’s disease induces microbiota pathogenicity contributing to mucosal inflammation. Guillaume Le Cosquer, Melissa Pannier, ..., Laura Guiraud, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, Gut Microbes 2026. DOI: 10.1080/19490976.2026.2687903

Updated *BJP* guidelines for transparent and rigorous natural product research. Xin Wang, Tayyiba Azam, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70420

Response to: Justifying and reporting the use of severe stress in experiments that use animals. Charles Whalley, Marie Anne Engh, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70411

Bidirectional associations between biological aging, cardiovascular health, and cardiovascular risk: findings from the INSPIRE-T lifespan cohort. Mathilde Strumia, Vanina Bongard, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., GeroScience 2026. DOI: 10.1007/s11357-026-02251-6

Accelerated Epigenetic and Inflammatory Aging and Intrinsic Capacity. Laure Rouch, Philipe de Souto Barreto, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., JAMA Network Open 2026. DOI: 10.1001/jamanetworkopen.2026.24102

Guidance on the planning and reporting of experimental design and analysis. Michael J. Curtis, S P H Alexander, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.17441

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review. Stavros Topouzis, Andreas Papapetropoulos, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.17458

Pharmacology of Intestinal Inflammation and Repair. Céline Deraison, Nathalie Vergnolle, Annual Review of Pharmacology and Toxicology 2025. DOI: 10.1146/annurev-pharmtox-051921-084536

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3. Mélissa David, Anaïs Faihy, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, British Journal of Pharmacology 2025. DOI: 10.1111/bph.70100

Pathogenicity of commensal gut biofilm in prefrail aging. Guillaume Le Cosquer, Melissa Pannier, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, et al., npj Biofilms and Microbiomes 2025. DOI: 10.1038/s41522-025-00716-8

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators. Arezoo Haghighi, András S. Tóth, ..., Jean‐Paul Motta, Nathalie Vergnolle, et al., Life Sciences 2025. DOI: 10.1016/j.lfs.2025.124114

Reporting innovations in pharmacology and drug development, upholding excellence and improving author experience at the *British Journal of Pharmacology* in 2024. Andreas Papapetropoulos, Evan E. Santo, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.70083

Modeling Postoperative Pathologic Ileus in Mice: A Simplified and Translational Approach. Romain Gauthier, Julie Thevenin, ..., Nathalie Vergnolle, ..., Céline Deraison, Neurogastroenterology & Motility 2025. DOI: 10.1111/nmo.70157

Evaluation of the prebiotic potential of polyphenol-rich plant extracts in a mouse model of colitis. Damien Guillemet, Perrine Rousset, ..., Anissa Edir, ..., Laura Guiraud, Nathalie Vergnolle, Jean‐Paul Motta, Microbiota and Host 2025. DOI: 10.1530/mah-25-0007

Human fallopian tube organoids provide a favourable environment for sperm motility. Nicolas Gatimel, G. Perez, ..., Céline Deraison, Jean‐Paul Motta, ..., Nathalie Vergnolle, Human Reproduction 2025. DOI: 10.1093/humrep/deae258

Proteases in intestinal health and disease. Céline Deraison, Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2025. DOI: 10.1038/s41575-025-01129-w

Next-generation enteric neuroscience — fostering the future of the field. Anoohya N. Muppirala, Mitchell Ringuet, ..., Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2025. DOI: 10.1038/s41575-025-01102-7

Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review. Andreas Papapetropoulos, Stavros Topouzis, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.16337

Molecular Mechanisms Underlying Loss of Vascular and Epithelial Integrity in Irritable Bowel Syndrome. Maria Raffaella Barbaro, Cesare Cremon, ..., Nathalie Vergnolle, et al., Gastroenterology 2024. DOI: 10.1053/j.gastro.2024.07.004

Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2. L Rondeau, B Barbosa da Luz, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Gut Microbes 2024. DOI: 10.1080/19490976.2024.2387857

Intestinal organoids to model Salmonella infection and its impact on progenitors. Yan Jin, Claire Racaud‐Sultan, ..., Anissa Edir, ..., Nathalie Vergnolle, Agnès Wiedemann, Scientific Reports 2024. DOI: 10.1038/s41598-024-65485-4

Gut microb-aging and its relevance to frailty aging. Guillaume Le Cosquer, Nathalie Vergnolle, Jean‐Paul Motta, Microbes and Infection 2024. DOI: 10.1016/j.micinf.2024.105309

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis. Nolwenn Laborde, Alexandre Barusseaud, ..., Nathalie Vergnolle, ..., Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas, The Journal of Pathology 2024. DOI: 10.1002/path.6366

Organoids, organs-on-chips, complex in vitro model: Definitions, applications, validation, ethics. Guillaume Mottet, Alexandre Grassart, ..., Nathalie Vergnolle, et al., Therapies 2024. DOI: 10.1016/j.therap.2024.12.002

Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms. Simon Guignard, Mahmoud Saifeddine, ..., Laura Guiraud, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, Chrystelle Bonnart, British Journal of Pharmacology 2024. DOI: 10.1111/bph.16341

The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer. Giulia Trimaglio, Tamara Sneperger, ..., Nathalie Vergnolle, et al., Scientific Reports 2024. DOI: 10.1038/s41598-024-57941-y

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate. Michelle Meng, Luke W Paine, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.17408

Thrombin stories in the gut. Nathalie Vergnolle, Biochimie 2024. DOI: 10.1016/j.biochi.2024.03.007

Mapping gut feelings and immune control. Nathalie Vergnolle, Science 2024. DOI: 10.1126/science.adq9533

BOC.04.4: THE GUT VASCULAR BARRIER IS IMPAIRED IN IRRITABLE BOWEL SYNDROME: IMPLICATIONS FOR SYMPTOM DEVELOPMENT. Maria Raffaella Barbaro, Cesare Cremon, ..., Nathalie Vergnolle, et al., Digestive and Liver Disease 2024. DOI: 10.1016/s1590-8658(24)00391-8

Organoïdes, organes sur puce, complex in vitro model : définitions, applications, validation, éthique. Guillaume Mottet, Alexandre Grassart, ..., Nathalie Vergnolle, et al., Therapies 2024. DOI: 10.1016/j.therap.2024.12.003

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Liwen Deng, Flavia G. Costa, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Cell 2023. DOI: 10.1016/j.cell.2023.10.019

Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives. Étienne Buscail, Guillaume Le Cosquer, ..., Céline Deraison, Nathalie Vergnolle, et al., International Journal of Molecular Sciences 2021. DOI: 10.3390/ijms22189967

Gastrointestinal biofilms in health and disease. Jean‐Paul Motta, John L. Wallace, ..., Céline Deraison, Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2021. DOI: 10.1038/s41575-020-00397-y

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients. Emilie d'Aldebert, Muriel Quaranta, ..., Claire Racaud‐Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle, Frontiers in Cell and Developmental Biology 2020. DOI: 10.3389/fcell.2020.00363

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. Florent Guerville, Philipe de Souto Barreto, ..., Nathalie Vergnolle, et al., The Journal of Prevention of Alzheimer's Disease 2020. DOI: 10.14283/jpad.2019.50

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats. Céline Augé, X. Gamé, Nathalie Vergnolle, et al., Frontiers in Pharmacology 2020. DOI: 10.3389/fphar.2020.01305

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Alberto Caminero, Justin L. McCarville, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Nature Communications 2019. DOI: 10.1038/s41467-019-09037-9

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner. Marion Rincel, P. Aubert, ..., Nathalie Vergnolle, et al., Brain, Behavior, and Immunity 2019. DOI: 10.1016/j.bbi.2019.03.006

Neurons and Glia in the Enteric Nervous System and Epithelial Barrier Function. Nathalie Vergnolle, Carla Cirillo, Physiology 2018. DOI: 10.1152/physiol.00009.2018

Protectin D1~n-3 DPA~ and resolvin D5~n-3 DPA~ are effectors of intestinal protection. Thomas Gobbetti, Jesmond Dalli, ..., Nathalie Vergnolle, Céline Deraison, et al., Proceedings of the National Academy of Sciences 2017. DOI: 10.1073/pnas.1617290114

Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Claire Rolland-Fourcade, Alexandre Denadai‐Souza, ..., Jean‐Paul Motta, ..., Céline Deraison, Nathalie Vergnolle, Gut 2017. DOI: 10.1136/gutjnl-2016-312094

The Intestinal Microenvironment and Functional Gastrointestinal Disorders. Giovanni Barbara, Christine Feinle‐Bisset, ..., Nathalie Vergnolle, et al., Gastroenterology 2016. DOI: 10.1053/j.gastro.2016.02.028

Protease inhibition as new therapeutic strategy for GI diseases. Nathalie Vergnolle, Gut 2016. DOI: 10.1136/gutjnl-2015-309147