Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury. Nina Colitti, Edwige Rice, ..., Nathalie Vergnolle, et al., Advanced Science 2026. DOI: 10.1002/advs.202503362

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review. Andreas Papapetropoulos, Stavros Topouzis, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70376

Comment un mécanisme de résistance aux antibiotiques favorise la virulence bactérienne. Audrey Goman, Lola Manenc, ..., Priscilla Branchu, et al., médecine/sciences 2026. DOI: 10.1051/medsci/2025252

Is Klebsiella pneumoniae -associated bovine mastitis an emerging public health issue? A One Health perspective. Delphine Payros, Frédéric Auvray, et al., ASM Animal Microbiology 2026. DOI: 10.1128/asmam.00023-25

β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., Journal of Biomedical Science 2026. DOI: 10.1186/s12929-026-01249-8

The role of dietary patterns on epigenetic and inflammatory aging based on the INSPIRE-T study. Natasha Grande de França, Yves Rolland, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., Communications Medicine 2026. DOI: 10.1038/s43856-026-01643-1

High thrombin activity associated with crohn’s disease induces microbiota pathogenicity contributing to mucosal inflammation. Guillaume Le Cosquer, Melissa Pannier, ..., Laura Guiraud, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, Gut Microbes 2026. DOI: 10.1080/19490976.2026.2687903

NLRP3 inflammasome partially mediates genotoxic E. coli infection in lean but not in genetically obese mice. Pauline Floch, Cécile Goursat, ..., Priscilla Branchu, et al., iScience 2026. DOI: 10.1016/j.isci.2026.116674

Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn’s disease susceptibility. Manon Dussol, Sandrine Ménard, ..., Frédérick Barreau, et al., Frontiers in Toxicology 2026. DOI: 10.3389/ftox.2026.1839932

Surmonter la complexité de CYP21A2 : une stratégie NGS optimisée pour le diagnostic moléculaire du déficit en 21-hydroxylase – à propos d’un cas clinique. Julie Milandri, Jean Monlong, et al., Annales d'Endocrinologie 2026. DOI: 10.1016/j.ando.2026.102540

Catestatin decreases duodenal hypermotility to improve glucose homeostasis in diabetic male mice. Anne Abot, Céline El Samrout, ..., Sarah Djebali, et al., Gut Science 2026. DOI: 10.1136/gutsci-2026-000021

A versatile multi-components mixed model for bacterial-Genome Wide association studies. Arthur Frouin, Fabien Laporte, et al., Nature Communications 2026. DOI: 10.1038/s41467-026-72305-y

Strigolactones and sesquiterpene lactones induce Orobanche cumana germination via KAI2d receptors through distinct processes. Julien Affholder, Louis Lambret, ..., Stéphane Muños, et al., The Plant Journal 2026. DOI: 10.1111/tpj.70852

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects. Claude Stoll, Yves Alembik, Marie‐Paule Roth, American Journal of Medical Genetics Part A 2026. DOI: 10.1002/ajmga.70002

Comment un mécanisme de résistance aux antibiotiques favorise la virulence bactérienne. Audrey Goman, Lola Manenc, ..., Priscilla Branchu, et al., https://doi.org/10.1051/medsci/2025252 2026. DOI: 10.1051/medsci/2025252/pdf

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model. Kawthar Boumessid, Vickie Lacroix, ..., Frédérick Barreau, Emmanuel Mas, Journal of Pediatric Gastroenterology and Nutrition 2026. DOI: 10.1002/jpn3.70517

A cell-nonautonomous heme acquisition pathway enables erythroid hemoglobinization under stress. Audrey Belot, Andrew Rock, et al., Science 2026. DOI: 10.1126/science.aea0552

Effect of 12 weeks with a 30-min nap opportunity during the night shift of healthcare workers on early cardiovascular risk biomarkers: the NAPWORK study protocol of a randomised controlled trial. Yanis Bouchou, Mathilde Monnier, ..., Mathieu Berger, BMJ Open 2026. DOI: 10.1136/bmjopen-2025-110108

Travail posté et santé vasculaire : revue des altérations de la fonction endothéliale et des biomarqueurs cardiovasculaires associés. Yanis Bouchou, Frederic Roche, ..., Mathieu Berger, Médecine du Sommeil 2026. DOI: 10.1016/j.msom.2025.12.073

Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment. Nathan Day, Baptiste Pradel, ..., Julien Vaubourgeix, et al., Nature Communications 2026. DOI: 10.1038/s41467-026-75915-8

Updated BJP guidelines for transparent and rigorous natural product research. Xin Wang, Tayyiba Azam, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70420

Response to: Justifying and reporting the use of severe stress in experiments that use animals. Charles Whalley, Marie Anne Engh, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2026. DOI: 10.1111/bph.70411

Bidirectional associations between biological aging, cardiovascular health, and cardiovascular risk: findings from the INSPIRE-T lifespan cohort. Mathilde Strumia, Vanina Bongard, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., GeroScience 2026. DOI: 10.1007/s11357-026-02251-6

Accelerated Epigenetic and Inflammatory Aging and Intrinsic Capacity. Laure Rouch, Philipe de Souto Barreto, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., JAMA Network Open 2026. DOI: 10.1001/jamanetworkopen.2026.24102

Additional file 1 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163842.v1

Additional file 2 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163845.v1

Additional file 3 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163848

Additional file 1 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163842

Additional file 3 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163848.v1

Additional file 2 of β-Sitosterol β-d-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onset. Francesca Terrin, Sofia Faggin, et al., 2026. DOI: 10.6084/m9.figshare.32163845

Guidance on the planning and reporting of experimental design and analysis. Michael J. Curtis, S P H Alexander, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.17441

Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection. Shloka Negi, Sarah L. Stenton, ..., Jean Monlong, et al., The American Journal of Human Genetics 2025. DOI: 10.1016/j.ajhg.2025.01.002

Empowering bioinformatics communities with Nextflow and nf-core. Björn E. Langer, Andreia Neves do Amaral, ..., Sarah Djebali, et al., Genome Biology 2025. DOI: 10.1186/s13059-025-03673-9

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review. Stavros Topouzis, Andreas Papapetropoulos, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.17458

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges. Asja Garling, Frédéric Auvray, ..., Éric Oswald, Priscilla Branchu, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70150

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. Arthur Mauduit, Emmanuel Mas, ..., Sandrine Ménard, Frédérick Barreau, Journal of Gastroenterology 2025. DOI: 10.1007/s00535-025-02289-x

Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals. Nicolas Jousserand, Frédéric Auvray, ..., Éric Oswald, Veterinary Research 2025. DOI: 10.1186/s13567-025-01493-0

Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria. Audrey Goman, Bérengère Ize, ..., Frédéric Taïeb, ..., Laure David, ..., Priscilla Branchu, Éric Oswald, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70032

Deciphering the interplay between biology and physics with a finite element method-implemented vertex organoid model: A tool for the mechanical analysis of cell behavior on a spherical organoid shell. Julien Laussu, Déborah Michel, ..., Frédérick Barreau, Emmanuel Mas, et al., PLOS Computational Biology 2025. DOI: 10.1371/journal.pcbi.1012681

Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli. Asja Garling, Cécile Goursat, ..., Jean‐Philippe Nougayrède, Éric Oswald, Frédéric Auvray, Priscilla Branchu, Vaccine 2025. DOI: 10.1016/j.vaccine.2025.126899

Dietary intake remains unchanged while nutritional status improves in children and adults with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor. Raphaël Enaud, Jeanne Languepin, ..., Emmanuel Mas, et al., Clinical Nutrition 2025. DOI: 10.1016/j.clnu.2025.04.027

Pharmacology of Intestinal Inflammation and Repair. Céline Deraison, Nathalie Vergnolle, Annual Review of Pharmacology and Toxicology 2025. DOI: 10.1146/annurev-pharmtox-051921-084536

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3. Mélissa David, Anaïs Faihy, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, British Journal of Pharmacology 2025. DOI: 10.1111/bph.70100

Evolution of hepatobiliary involvement in cystic fibrosis children on CFTR modulators. Mélanie Auvray, Nolwenn Laborde, ..., Frédérick Barreau, ..., Emmanuel Mas, Journal of Cystic Fibrosis 2025. DOI: 10.1016/j.jcf.2025.05.003

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis. Thanina Medjbeur, Ugo Sardo, ..., Léon Kautz, FASEB BioAdvances 2025. DOI: 10.1096/fba.2025-00022

Pathogenicity of commensal gut biofilm in prefrail aging. Guillaume Le Cosquer, Melissa Pannier, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, et al., npj Biofilms and Microbiomes 2025. DOI: 10.1038/s41522-025-00716-8

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators. Arezoo Haghighi, András S. Tóth, ..., Jean‐Paul Motta, Nathalie Vergnolle, et al., Life Sciences 2025. DOI: 10.1016/j.lfs.2025.124114

Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets. Smahane Chalabi, Linda M. P. Loonen, ..., Sarah Djebali, et al., Genomics 2025. DOI: 10.1016/j.ygeno.2025.110995

Polygenic risk score prediction accuracy convergence. Léo Henches, Jihye Kim, ..., Arthur Frouin, ..., Sarah Djebali, et al., Human Genetics and Genomics Advances 2025. DOI: 10.1016/j.xhgg.2025.100457

Ablation of Hepatocyte Derived‐FGL1 Does Not Aggravate Metabolic Dysfunction‐Associated Steatotic Liver Disease. Jean Personnaz, Lisa Cannizzo, ..., Aurore Desquesnes, ..., Léon Kautz, The FASEB Journal 2025. DOI: 10.1096/fj.202501997r

Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling. Alexis Audibert, Xavier Mas‐Orea, ..., Chrystelle Bonnart, et al., PLOS Pathogens 2025. DOI: 10.1371/journal.ppat.1013106

Reporting innovations in pharmacology and drug development, upholding excellence and improving author experience at the British Journal of Pharmacology in 2024. Andreas Papapetropoulos, Evan E. Santo, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.70083

A Non-genotoxic Variant of Escherichia coli Nissle 1917 EcN 2.0 Overexpressing Microcins Reduces Intestinal Carriage of ST131 ESBL-Producing Escherichia coli. Nicolas Jousserand, Benjamin Massiera, ..., Éric Oswald, et al., Probiotics and Antimicrobial Proteins 2025. DOI: 10.1007/s12602-025-10777-y

Intestinal involvement in graft versus host disease in children: An overview by the ESPGHAN Gastroenterology Committee. Marina Vincent, Amit Assa, ..., Emmanuel Mas, Journal of Pediatric Gastroenterology and Nutrition 2025. DOI: 10.1002/jpn3.70087

Modeling Postoperative Pathologic Ileus in Mice: A Simplified and Translational Approach. Romain Gauthier, Julie Thevenin, ..., Nathalie Vergnolle, ..., Céline Deraison, Neurogastroenterology & Motility 2025. DOI: 10.1111/nmo.70157

Opinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the assessment of the impact of fox population dynamics on public health. Emmanuelle Gilot‐Fromont, Isabelle Villena, ..., Frédéric Auvray, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0062

Maternal regulation of iron metabolism resolved?. Léon Kautz, Blood 2025. DOI: 10.1182/blood.2025029469

Studying Pseudomonas aeruginosa pathogenesis: the need for more than just the PAO1 strain. Laure David, Audrey Goman, ..., Frédéric Taïeb, Priscilla Branchu, Éric Oswald, Microbiology Spectrum 2025. DOI: 10.1128/spectrum.00665-25

Stabilization of G-Quadruplexes Modulates the Expression of DNA Damage and Unfolded Protein Response Genes in Canine Lymphoma/Leukemia Cells. Beatriz Hernández‐Suárez, David A. Gillespie, et al., International Journal of Molecular Sciences 2025. DOI: 10.3390/ijms26209928

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders. Sohail Aziz, Maria Giovanna Puoti, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2025. DOI: 10.1002/jpn3.70245

Emergence and genetic heterogeneity of STEC O113:H4: insights from whole-genome sequences of isolates across human and non-human sources. Florence Crombé, Frédéric Auvray, et al., International Journal of Medical Microbiology 2025. DOI: 10.1016/j.ijmm.2025.151688

Guiding eQTL mapping and genomic prediction of gene expression in three pig breeds with tissue-specific epigenetic annotations from early development. Fanny Mollandin, Hervé Acloque, ..., Sarah Djebali, et al., Genomics 2025. DOI: 10.1016/j.ygeno.2025.111158

Residual antimicrobials in food can select for antimicrobial resistance. Elissa Khamisse, Xavier Bertrand, ..., Éric Oswald, The Lancet Microbe 2025. DOI: 10.1016/j.lanmic.2025.101302

Kinetics of molecular patterns captured by mannose-binding lectin in septic shock correlate with clinical outcome: a monocentric prospective observational study. A. Bicart-See, Fanny Vardon‐Bounes, ..., Éric Oswald, Intensive Care Medicine Experimental 2025. DOI: 10.1186/s40635-025-00832-x

Evaluation of the prebiotic potential of polyphenol-rich plant extracts in a mouse model of colitis. Damien Guillemet, Perrine Rousset, ..., Anissa Edir, ..., Laura Guiraud, Nathalie Vergnolle, Jean‐Paul Motta, Microbiota and Host 2025. DOI: 10.1530/mah-25-0007

Single-cell omics uncover gene dynamics shaping embryonic and extra embryonic lineages in pig blastocysts. Adrien Dufour, Marie-Noëlle M.-N. Rossignol, ..., Sarah Djebali, et al., iScience 2025. DOI: 10.1016/j.isci.2025.114519

The influence of environment on bacterial co-abundance in the gut microbiomes of healthy human individuals. Christophe Boetto, Violeta Basten Romero, ..., Arthur Frouin, et al., Communications Biology 2025. DOI: 10.1038/s42003-025-08895-y

Co-occurring non-urinary congenital anomalies among cases with congenital anomalies of the kidney and urinary tract. Claude Stoll, Béatrice Dott, ..., Marie‐Paule Roth, European Journal of Medical Genetics 2025. DOI: 10.1016/j.ejmg.2025.105000

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, S. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Humans as a potential reservoir for the emerging ST301 Shiga toxin-producing Escherichia coli clones of serotype O80:H2?. Frédéric Auvray, Federica Gigliucci, ..., Éric Oswald, Clinical Microbiology and Infection 2025. DOI: 10.1016/j.cmi.2025.05.018

Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy. Marine Colson, Arthur Aubry, ..., Éric Oswald, Laure David, Cancer Gene Therapy 2025. DOI: 10.1038/s41417-025-00984-8

Assessing heart rate fragmentation to predict atrial fibrillation in the general population aged 65: the PROOF-AF study. Jean-Baptiste Guichard, David Hupin, ..., Mathieu Berger, et al., European Heart Journal Open 2025. DOI: 10.1093/ehjopen/oeaf030

Barriers and Levers to the Implementation of Napping During Night Shift Work in Healthcare Workers: A Qualitative Study in a French University Hospital. Maryame Mazouz, Pauline Gouttefarde, ..., Mathieu Berger, Journal of Nursing Management 2025. DOI: 10.1155/jonm/5279651

Fundamentos de fisiología del esfuerzo: adaptaciones cardíacas, vasculares y respiratorias. Pierre Labeix, M. Fanget, Mathieu Berger, EMC - Kinesiterapia - Medicina Física 2025. DOI: 10.1016/s1293-2965(24)49904-0

Basi di fisiologia dello sforzo: adattamenti cardiaci, vascolari e respiratori. Pierre Labeix, M. Fanget, Mathieu Berger, EMC - Medicina Riabilitativa 2025. DOI: 10.1016/s1283-078x(24)50008-6

Intérêt des paramètres hypoxémiques du Holter cardiorespiratoire dans le post-AVC ischémique pour le dépistage des pathologies respiratoires du sommeil. Marie Roux, Pierre Garnier, ..., Mathieu Berger, et al., Médecine du Sommeil 2025. DOI: 10.1016/j.msom.2025.01.005

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on defining pathogenic strains of Shiga toxin‐producing Escherichia coli. Philippe Fravalo, Frédéric Auvray, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0065

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the risks associated with the consumption of nitrites and nitrates. Marie‐Louise Scippo, Pierre‐Marie Badot, ..., Frédéric Auvray, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0059

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the presence of Toxocara spp. parasites in wild boar meat. Philippe Fravalo, Frédéric Auvray, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0058

Human fallopian tube organoids provide a favourable environment for sperm motility. Nicolas Gatimel, G. Perez, ..., Céline Deraison, Jean‐Paul Motta, ..., Nathalie Vergnolle, Human Reproduction 2025. DOI: 10.1093/humrep/deae258

Proteases in intestinal health and disease. Céline Deraison, Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2025. DOI: 10.1038/s41575-025-01129-w

Next-generation enteric neuroscience — fostering the future of the field. Anoohya N. Muppirala, Mitchell Ringuet, ..., Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2025. DOI: 10.1038/s41575-025-01102-7

RNA G-quadruplexes control mitochondria-localized mRNA translation and energy metabolism. Leïla Dumas, Sauyeun Shin, ..., Beatriz Hernández‐Suárez, et al., Nature Communications 2025. DOI: 10.1038/s41467-025-58118-5

Toll‐like receptor 4 deficiency ameliorates experimental ileitis and enteric neuropathy: Involvement of nitrergic and 5‐hydroxytryptaminergic neurotransmission. Sofia Faggin, Silvia Cerantola, et al., British Journal of Pharmacology 2025. DOI: 10.1111/bph.17439

Sex-dependent alteration of the enteric neuromuscular function after antibiotic-induced dysbiosis in juvenile mice and effect of Lactocaseibacillus rhamnosus GG. Annalisa Bosi, Davide Banfi, ..., Sofia Faggin, et al., Biomedicine & Pharmacotherapy 2025. DOI: 10.1016/j.biopha.2025.118263

Small Intestine Neuromuscular Dysfunctions and Neurogliopathy in a Mouse Model of High-Fat Diet-Induced Obesity: Involvement of Toll-Like Receptor 4. Sofia Faggin, Silvia Cerantola, et al., International Journal of Molecular Sciences 2025. DOI: 10.3390/ijms262110710

Development and Validation of an Escape Game for Food Safety Education: Gamifying the Management of a Food-Borne Health Alert. Pedro Henrique Didimo Imazaki, Carla Lewandowski, ..., Laure David, Journal of Veterinary Medical Education 2025. DOI: 10.3138/jvme-2024-0151

Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References. Dylan J. Taylor, Jordan M. Eizenga, ..., Jean Monlong, et al., Annual Review of Genomics and Human Genetics 2024. DOI: 10.1146/annurev-genom-021623-081639

Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review. Andreas Papapetropoulos, Stavros Topouzis, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.16337

Molecular Mechanisms Underlying Loss of Vascular and Epithelial Integrity in Irritable Bowel Syndrome. Maria Raffaella Barbaro, Cesare Cremon, ..., Nathalie Vergnolle, et al., Gastroenterology 2024. DOI: 10.1053/j.gastro.2024.07.004

Personalized pangenome references. Jouni Sirén, Parsa Eskandar, ..., Jean Monlong, et al., Nature Methods 2024. DOI: 10.1038/s41592-024-02407-2

Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2. L Rondeau, B Barbosa da Luz, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Gut Microbes 2024. DOI: 10.1080/19490976.2024.2387857

The microbiota and the host organism switch between cooperation and competition based on dietary iron levels. Marie-Louise Noordine, Yohannes Seyoum, ..., François Canonne‐Hergaux, et al., Gut Microbes 2024. DOI: 10.1080/19490976.2024.2361660

Intestinal organoids to model Salmonella infection and its impact on progenitors. Yan Jin, Claire Racaud‐Sultan, ..., Anissa Edir, ..., Nathalie Vergnolle, Agnès Wiedemann, Scientific Reports 2024. DOI: 10.1038/s41598-024-65485-4

Trends in horizontal gene transfer research in Salmonella antimicrobial resistance: a bibliometric analysis. Yan Jin, Benoît Doublet, Agnès Wiedemann, Frontiers in Microbiology 2024. DOI: 10.3389/fmicb.2024.1439664

Gut microb-aging and its relevance to frailty aging. Guillaume Le Cosquer, Nathalie Vergnolle, Jean‐Paul Motta, Microbes and Infection 2024. DOI: 10.1016/j.micinf.2024.105309

Functionality integration in stereolithography 3D printed microfluidics using a “print-pause-print” strategy. Matthieu Sagot, Timothée Derkenne, ..., Jean‐Philippe Nougayrède, et al., Lab on a Chip 2024. DOI: 10.1039/d4lc00147h

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis. Nolwenn Laborde, Alexandre Barusseaud, ..., Nathalie Vergnolle, ..., Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas, The Journal of Pathology 2024. DOI: 10.1002/path.6366

The Salmonella virulence protein PagN contributes to the advent of a hyper-replicating cytosolic bacterial population. Sébastien Holbert, Émilie Barilleau, ..., Agnès Wiedemann, Virulence 2024. DOI: 10.1080/21505594.2024.2357670

Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment. Yan Jin, Jean Monlong, ..., Agnès Wiedemann, Veterinary Research 2024. DOI: 10.1186/s13567-024-01333-7

Organoids, organs-on-chips, complex in vitro model: Definitions, applications, validation, ethics. Guillaume Mottet, Alexandre Grassart, ..., Nathalie Vergnolle, et al., Therapies 2024. DOI: 10.1016/j.therap.2024.12.002

A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice. Matthew Wake, Anaïs Palin, Audrey Belot, Mathieu Berger, ..., Céline Besson‐Fournier, Chloé Latour, ..., Hélène Coppin, Marie‐Paule Roth, ..., Delphine Meynard, Blood Advances 2024. DOI: 10.1182/bloodadvances.2023012010

Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms. Simon Guignard, Mahmoud Saifeddine, ..., Laura Guiraud, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, Chrystelle Bonnart, British Journal of Pharmacology 2024. DOI: 10.1111/bph.16341

Fibrinogen‐like 1: A hepatokine linking liver physiology to hematology. Jean Personnaz, Hervé Guillou, Léon Kautz, HemaSphere 2024. DOI: 10.1002/hem3.115

The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer. Giulia Trimaglio, Tamara Sneperger, ..., Nathalie Vergnolle, et al., Scientific Reports 2024. DOI: 10.1038/s41598-024-57941-y

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate. Michelle Meng, Luke W Paine, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.17408

Human tetraspanin CD81 facilitates invasion of Salmonella enterica into human epithelial cells. Kris Gerard Alvarez, Lisa Goral, ..., Agnès Wiedemann, et al., Virulence 2024. DOI: 10.1080/21505594.2024.2399792

Intestinal Carriage of Two Distinct stx2f-Carrying Escherichia coli Strains by a Child with Uncomplicated Diarrhea. Florence Crombé, Angela H. A. M. van Hoek, ..., Frédéric Auvray, et al., Pathogens 2024. DOI: 10.3390/pathogens13111002

Thrombin stories in the gut. Nathalie Vergnolle, Biochimie 2024. DOI: 10.1016/j.biochi.2024.03.007

FGL1, une nouvelle cible pour le traitement de l’anémie ?. Thanina Medjbeur, Jean Personnaz, Léon Kautz, médecine/sciences 2024. DOI: 10.1051/medsci/2024123

Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring. Elena Kuzmin, Toby M. Baker, ..., Jean Monlong, et al., Cell Reports 2024. DOI: 10.1016/j.celrep.2024.113988

P821: Long-read sequencing resolves CYP21A2 alleles in congenital adrenal hyperplasia*. Emmanuèle C. Délot, Jean Monlong, et al., Genetics in Medicine Open 2024. DOI: 10.1016/j.gimo.2024.101732

Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes. Lukas Hafner, Enzo Gadin, ..., Arthur Frouin, et al., Nature Microbiology 2024. DOI: 10.1038/s41564-024-01859-8

MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data. Christophe Boetto, Arthur Frouin, et al., Briefings in Bioinformatics 2024. DOI: 10.1093/bib/bbae272

Multitrait Analysis to Decipher the Intertwined Genetic Architecture of Neuroanatomical Phenotypes and Psychiatric Disorders. Antoine Auvergne, Nicolas Traut, ..., Arthur Frouin, et al., Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 2024. DOI: 10.1016/j.bpsc.2024.08.018

Development and characterization of a new sunflower source of resistance to race G of Orobanche cumana Wallr. derived from Helianthus anomalus. Belén Fernández-Melero, Lidia del Moral, ..., Stéphane Muños, et al., Theoretical and Applied Genetics 2024. DOI: 10.1007/s00122-024-04558-4

Mapping an avirulence gene in the sunflower parasitic weed Orobanche cumana and characterization of host selection based on virulence alleles. Álvaro Calderón-González, Belén Fernández-Melero, ..., Stéphane Muños, et al., BMC Plant Biology 2024. DOI: 10.1186/s12870-024-05855-2

microRNA‐encoded peptides inhibit seed germination of the root parasitic plant Orobanche cumana. Sabine Tourneur, Jean‐Philippe Combier, ..., Stéphane Muños, et al., PLANTS, PEOPLE, PLANET 2024. DOI: 10.1002/ppp3.10501

A cluster of putative resistance genes is associated with a dominant resistance to sunflower broomrape. Camille Pubert, Marie‐Claude Boniface, ..., Stéphane Muños, Theoretical and Applied Genetics 2024. DOI: 10.1007/s00122-024-04594-0

Associated Anomalies in Radial Ray Deficiency. Claude Stoll, Yves Alembik, Marie‐Paule Roth, American Journal of Medical Genetics Part A 2024. DOI: 10.1002/ajmg.a.63874

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Julie Thevenin, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

Anatomy and physiology of the autonomic nervous system: Implication on the choice of diagnostic/monitoring tools in 2023. Frédéric Roche, Vincent Pichot, ..., Mathieu Berger, et al., Revue Neurologique 2024. DOI: 10.1016/j.neurol.2023.12.003

Sleep disturbances and incident risk of major depressive disorder in a population-based cohort. Geoffroy Solelhac, Théo Imler, ..., Mathieu Berger, et al., Psychiatry Research 2024. DOI: 10.1016/j.psychres.2024.115934

Sleep Habits and Disturbances in Healthcare Workers: A Cross-Sectional Survey in French Public Hospitals. Yanis Bouchou, Lorine Giffard-Quillon, ..., Mathieu Berger, Nature and Science of Sleep 2024. DOI: 10.2147/nss.s461993

The Frame Analysis of Participation: A Goffmanian Take on Democratic Interaction and its Ambiguities. Mathieu Berger, Symbolic Interaction 2024. DOI: 10.1002/symb.1211

An AI-based approach for detecting COVID-19 long-haul patients through sleep polysomnography analysis: the pandore-IA project. Hugo Lerogeron, Anis Aloulou, ..., Mathieu Berger, et al., Sleep Medicine 2024. DOI: 10.1016/j.sleep.2023.11.456

Prediction of driving performance on simulator using clinical and sleep parameters: The PANDORE-IA project. Miriam Benballa, Mathieu Berger, et al., Sleep Medicine 2024. DOI: 10.1016/j.sleep.2023.11.245

Association entre sommeil et risque prospectif de trouble dépressif majeur (TDM) dans la cohorte de population générale CoLaus|HypnoLaus. Geoffroy Solelhac, Théo Imler, ..., Mathieu Berger, et al., Médecine du Sommeil 2024. DOI: 10.1016/j.msom.2023.12.019

La sieste au travail : freins et leviers à l’implémentation d’une salle de sieste en milieu hospitalier pour les soignants en poste de 12 h alternant. Maryame Mazouz, Pauline Gouttefarde, ..., Mathieu Berger, Médecine du Sommeil 2024. DOI: 10.1016/j.msom.2023.12.184

Insomnie et COVID long : une analyse assistée par l’IA pour explorer la microarchitecture du sommeil des patients. Hugo Lerogeron, Anis Aloulou, ..., Mathieu Berger, et al., Médecine du Sommeil 2024. DOI: 10.1016/j.msom.2023.12.013

Évolution du syndrome d’apnée du sommeil entre 68 et 85 ans et relation avec l’activité autonomique (cohorte PROOF-SYNAPSE). Vincent Pichot, Mathieu Berger, et al., Médecine du Sommeil 2024. DOI: 10.1016/j.msom.2023.12.007

PO-03-088 ASSESSING HEART RATE FRAGMENTATION TO PREDICT ATRIAL FIBRILLATION IN THE GENERAL POPULATION AGED 65. Jean-Baptiste Guichard, David Hupin, ..., Mathieu Berger, et al., Heart Rhythm 2024. DOI: 10.1016/j.hrthm.2024.03.1089

Qualité et habitudes de sommeil des soignants du GHT Loire. Yanis Bouchou, Lorine Riffart, ..., Mathieu Berger, Archives des Maladies Professionnelles et de l'Environnement 2024. DOI: 10.1016/j.admp.2024.102582

Évaluation des habitudes de sommeil des soignants en fonction du rythme de travail : une étude transversale monocentrique. Lorine Giffard-Quillon, Yanis Bouchou, ..., Mathieu Berger, et al., Archives des Maladies Professionnelles et de l'Environnement 2024. DOI: 10.1016/j.admp.2024.102055

The Positive Impact of Virulence Genes in Bacterial Pathogenicity and Colonization on the Large Bowel in Colorectal Cancer Patients. Mohammad Khalilolahi, Fatemeh Ashrafi, ..., Jean‐Philippe Nougayrède, et al., Iranian Journal of Blood and Cancer 2024. DOI: 10.61186/ijbc.16.3.63

Monkeypox Clade II en France en 2023 : une situation endémique ?. Mayda Rahi, Marie Gilbert, ..., Frédéric Taïeb, et al., Médecine et Maladies Infectieuses Formation 2024. DOI: 10.1016/j.mmifmc.2024.04.019

Mapping gut feelings and immune control. Nathalie Vergnolle, Science 2024. DOI: 10.1126/science.adq9533

BOC.04.4: THE GUT VASCULAR BARRIER IS IMPAIRED IN IRRITABLE BOWEL SYNDROME: IMPLICATIONS FOR SYMPTOM DEVELOPMENT. Maria Raffaella Barbaro, Cesare Cremon, ..., Nathalie Vergnolle, et al., Digestive and Liver Disease 2024. DOI: 10.1016/s1590-8658(24)00391-8

Organoïdes, organes sur puce, complex in vitro model : définitions, applications, validation, éthique. Guillaume Mottet, Alexandre Grassart, ..., Nathalie Vergnolle, et al., Therapies 2024. DOI: 10.1016/j.therap.2024.12.003

Predictive Capacity of the Integrated Care for Older People Screening Tool for Intrinsic Capacity Impairments: Results From the INSPIRE-T Cohort. Kelly Virecoulon Giudici, Philipe de Souto Barreto, ..., Jean‐Paul Motta, et al., The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 2024. DOI: 10.1093/gerona/glae112

Safety of potassium-competitive acid blockers in the treatment of gastroesophageal reflux disease. Angela Tietto, Sofia Faggin, et al., Expert Opinion on Drug Metabolism & Toxicology 2024. DOI: 10.1080/17425255.2024.2397433

Cold-induced thermogenesis requires neutral-lipase-mediated intracellular lipolysis in brown adipocytes. Étienne Mouisel, A Bodon, ..., Stéphanie Cassant‐Sourdy, et al., Cell Metabolism 2024. DOI: 10.1016/j.cmet.2024.10.018

Rôle sexuellement dimorphique du récepteur aux œstrogènes ER alpha hépatocytaire dans la progression vers la stéato-hépatite métabolique. Blandine Tramunt, Marie-Lou Calmy, ..., Stéphanie Cassant‐Sourdy, et al., Annales d'Endocrinologie 2024. DOI: 10.1016/j.ando.2024.08.090

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Liwen Deng, Flavia G. Costa, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Cell 2023. DOI: 10.1016/j.cell.2023.10.019

Pediatric Magnet Ingestion, Diagnosis, Management, and Prevention. Ahmed Nugud, Christos Tzivinikos, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2023. DOI: 10.1097/mpg.0000000000003702

Differential Salmonella Typhimurium intracellular replication and host cell responses in caecal and ileal organoids derived from chicken. Sonia Lacroix‐Lamandé, Ophélie Bernardi, ..., Agnès Wiedemann, Veterinary Research 2023. DOI: 10.1186/s13567-023-01189-3

A draft human pangenome reference. Wen‐Wei Liao, Mobin Asri, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05896-x

Pangenome graph construction from genome alignments with Minigraph-Cactus. Glenn Hickey, Jean Monlong, et al., Nature Biotechnology 2023. DOI: 10.1038/s41587-023-01793-w

Recombination between heterologous human acrocentric chromosomes. Andrea Guarracino, Silvia Buonaiuto, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05976-y

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Mikhail Kolmogorov, Kimberley J. Billingsley, ..., Jean Monlong, et al., Nature Methods 2023. DOI: 10.1038/s41592-023-01993-x

Increased mutation and gene conversion within human segmental duplications. Mitchell R. Vollger, Philip C. Dishuck, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05895-y

A draft human pangenome reference. Wen‐Wei Liao, Mobin Asri, ..., Jean Monlong, et al., Yearbook of Paediatric Endocrinology 2023. DOI: 10.1530/ey.20.12.1

The genomics of linkage drag in inbred lines of sunflower. Kaichi Huang, Mojtaba Jahani, ..., Stéphane Muños, et al., Proceedings of the National Academy of Sciences 2023. DOI: 10.1073/pnas.2205783119

Associated anomalies inPierre Robin sequence. Claude Stoll, Yves Alembick, Marie‐Paule Roth, American Journal of Medical Genetics Part A 2023. DOI: 10.1002/ajmg.a.63344

Obstructive sleep apnoea and 5-year cognitive decline in the elderly. Nicola Andrea Marchi, Geoffroy Solelhac, Mathieu Berger, et al., European Respiratory Journal 2023. DOI: 10.1183/13993003.01621-2022

Pulse Wave Amplitude Drops Index: A Biomarker of Cardiovascular Risk in Obstructive Sleep Apnea. Geoffroy Solelhac, Manuel Sánchez‐de‐la‐Torre, ..., Mathieu Berger, et al., American Journal of Respiratory and Critical Care Medicine 2023. DOI: 10.1164/rccm.202206-1223oc

Objective polysomnography-based sleep features and major depressive disorder subtypes in the general population. Geoffroy Solelhac, Mathieu Berger, et al., Psychiatry Research 2023. DOI: 10.1016/j.psychres.2023.115213

From ribosome to ribotoxins: understanding the toxicity of deoxynivalenol and Shiga toxin, two food borne toxins. Marion Garofalo, Delphine Payros, Frédéric Taïeb, ..., Jean‐Philippe Nougayrède, et al., Critical Reviews in Food Science and Nutrition 2023. DOI: 10.1080/10408398.2023.2271101

O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases. Aurore Labourel, Jean‐Luc Parrou, Céline Deraison, et al., Essays in Biochemistry 2023. DOI: 10.1042/ebc20220153

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity. Anne Fougerat, Gabriele Schoiswohl, ..., Delphine Meynard, et al., Cell Reports 2022. DOI: 10.1016/j.celrep.2022.110910

Postoperative ileus: A pharmacological perspective. Étienne Buscail, Céline Deraison, British Journal of Pharmacology 2022. DOI: 10.1111/bph.15800

Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation. Laure David, Frédéric Taïeb, ..., Éric Oswald, Autophagy 2022. DOI: 10.1080/15548627.2022.2054040

Cross-Talk Between the Intestinal Epithelium and Salmonella Typhimurium. Sandrine Ménard, Sonia Lacroix‐Lamandé, ..., Agnès Wiedemann, Frontiers in Microbiology 2022. DOI: 10.3389/fmicb.2022.906238

Identification of bacterial lipopeptides as key players in IBS. Camille Petitfils, Sarah Maurel, ..., Frédéric Auvray, ..., Jean‐Paul Motta, ..., Éric Oswald, et al., Gut 2022. DOI: 10.1136/gutjnl-2022-328084

Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting. John E. Gorzynski, Sneha D. Goenka, ..., Jean Monlong, et al., New England Journal of Medicine 2022. DOI: 10.1056/nejmc2112090

Accelerated identification of disease-causing variants with ultra-rapid nanopore genome sequencing. Sneha D. Goenka, John E. Gorzynski, ..., Jean Monlong, et al., Nature Biotechnology 2022. DOI: 10.1038/s41587-022-01221-5

Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells. Charles Couturier, Javad Nadaf, ..., Jean Monlong, et al., Neuro-Oncology 2022. DOI: 10.1093/neuonc/noac085

Identification of risk loci for primary aldosteronism in genome-wide association studies. Édith Le Floch, Teresa Cosentino, ..., Arthur Frouin, et al., Nature Communications 2022. DOI: 10.1038/s41467-022-32896-8

The ecologically relevant genetics of plant–plant interactions. Claude Becker, Richard Berthomé, ..., Stéphane Muños, et al., Trends in Plant Science 2022. DOI: 10.1016/j.tplants.2022.08.014

The pks island: a bacterial Swiss army knife? Colibactin: beyond DNA damage and cancer. Camille V. Chagneau, Delphine Payros, ..., Frédéric Auvray, Jean‐Philippe Nougayrède, Éric Oswald, Trends in Microbiology 2022. DOI: 10.1016/j.tim.2022.05.010

Role of milk and milk products in the spread of methicillin‐resistant Staphylococcus aureus in the dairy production chain. Yacine Titouche, Madjid Akkou, ..., Frédéric Auvray, et al., Journal of Food Science 2022. DOI: 10.1111/1750-3841.16259

Respiratory syncytial virus ribonucleoproteins hijack microtubule Rab11 dependent transport for intracellular trafficking. Gina Cosentino, Katherine Marougka, Aurore Desquesnes, et al., PLOS Pathogens 2022. DOI: 10.1371/journal.ppat.1010619

Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood. Amani Mubarak, Marc A. Benninga, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2021. DOI: 10.1097/mpg.0000000000003048

Effects of Hydrogen Sulfide on the Microbiome: From Toxicity to Therapy. André G. Buret, Thibault Allain, Jean‐Paul Motta, et al., Antioxidants & Redox Signaling 2021. DOI: 10.1089/ars.2021.0004

Intestinal organoids in farm animals. Martín Beaumont, Fany Blanc, ..., Agnès Wiedemann, Veterinary Research 2021. DOI: 10.1186/s13567-021-00909-x

A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917. Jean‐Philippe Nougayrède, Camille V. Chagneau, Jean‐Paul Motta, ..., Frédéric Taïeb, ..., Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00624-21

Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives. Étienne Buscail, Guillaume Le Cosquer, ..., Céline Deraison, Nathalie Vergnolle, et al., International Journal of Molecular Sciences 2021. DOI: 10.3390/ijms22189967

Gastrointestinal Perspective of Coronavirus Disease 2019 in Children—An Updated Review. Amit Assa, Marc A. Benninga, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2021. DOI: 10.1097/mpg.0000000000003204

Pangenomics enables genotyping of known structural variants in 5202 diverse genomes. Jouni Sirén, Jean Monlong, et al., Science 2021. DOI: 10.1126/science.abg8871

RNA-Seq Data for Reliable SNP Detection and Genotype Calling: Interest for Coding Variant Characterization and Cis-Regulation Analysis by Allele-Specific Expression in Livestock Species. Frédéric Jehl, Fabien Degalez, ..., Sarah Djebali, et al., Frontiers in Genetics 2021. DOI: 10.3389/fgene.2021.655707

Gastrointestinal biofilms in health and disease. Jean‐Paul Motta, John L. Wallace, ..., Céline Deraison, Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2021. DOI: 10.1038/s41575-020-00397-y

A condensate-hardening drug blocks RSV replication in vivo. Jennifer Risso-Ballester, Marie Galloux, ..., Aurore Desquesnes, et al., Nature 2021. DOI: 10.1038/s41586-021-03703-z

Expanded encyclopaedias of DNA elements in the human and mouse genomes. Federico Abascal, Reyes Acosta, ..., Sarah Djebali, et al., Nature 2020. DOI: 10.1038/s41586-020-2493-4

Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes. Kishwar Shafin, Trevor Pesout, ..., Jean Monlong, et al., Nature Biotechnology 2020. DOI: 10.1038/s41587-020-0503-6

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy. Charles Couturier, Shamini Ayyadhury, ..., Jean Monlong, et al., Nature Communications 2020. DOI: 10.1038/s41467-020-17186-5

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Bernardo Rodríguez–Martín, Eva G. Alvarez, ..., Jean Monlong, et al., Nature Genetics 2020. DOI: 10.1038/s41588-019-0562-0

Genotyping structural variants in pangenome graphs using the vg toolkit. Glenn Hickey, David N. Heller, Jean Monlong, et al., Genome Biology 2020. DOI: 10.1186/s13059-020-1941-7

Genetic effects on gene expression across human tissues. Eric Haugen, Yuan He, ..., Jean Monlong, et al., 2020. DOI: 10.17615/p82n-gb73

Perspectives on ENCODE. Federico Abascal, Reyes Acosta, ..., Sarah Djebali, et al., Nature 2020. DOI: 10.1038/s41586-020-2449-8

Massive haplotypes underlie ecotypic differentiation in sunflowers. Marco Todesco, Gregory L. Owens, ..., Stéphane Muños, et al., Nature 2020. DOI: 10.1038/s41586-020-2467-6

Gene banks for wild and cultivated sunflower genetic resources. S. Terzić, Marie‐Claude Boniface, ..., Stéphane Muños, et al., OCL 2020. DOI: 10.1051/ocl/2020004

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis. Julien Pujo, Camille Petitfils, ..., Frédérick Barreau, ..., Éric Oswald, et al., Gut 2020. DOI: 10.1136/gutjnl-2020-321173

Psychological Stress, Intestinal Barrier Dysfunctions, and Autoimmune Disorders: An Overview. Hanna Ilchmann-Diounou, Sandrine Ménard, Frontiers in Immunology 2020. DOI: 10.3389/fimmu.2020.01823

The food contaminant, deoxynivalenol, modulates the Thelper/Treg balance and increases inflammatory bowel diseases. Delphine Payros, Sandrine Ménard, et al., Archives of Toxicology 2020. DOI: 10.1007/s00204-020-02817-z

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients. Emilie d'Aldebert, Muriel Quaranta, ..., Claire Racaud‐Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle, Frontiers in Cell and Developmental Biology 2020. DOI: 10.3389/fcell.2020.00363

Biology of antimicrobial resistance and approaches to combat it. Sarah Schrader, Julien Vaubourgeix, et al., Science Translational Medicine 2020. DOI: 10.1126/scitranslmed.aaz6992

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. Florent Guerville, Philipe de Souto Barreto, ..., Nathalie Vergnolle, et al., The Journal of Prevention of Alzheimer's Disease 2020. DOI: 10.14283/jpad.2019.50

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats. Céline Augé, X. Gamé, Nathalie Vergnolle, et al., Frontiers in Pharmacology 2020. DOI: 10.3389/fphar.2020.01305

FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer. Sonia Zaghdoudi, Emilie Decaup, ..., Stéphanie Cassant‐Sourdy, et al., EMBO Molecular Medicine 2020. DOI: 10.15252/emmm.202012010

Stalled developmental programs at the root of pediatric brain tumors. Selin Jessa, Alexis Blanchet-Cohen, ..., Jean Monlong, et al., Nature Genetics 2019. DOI: 10.1038/s41588-019-0531-7

Multi-species annotation of transcriptome and chromatin structure in domesticated animals. Sylvain Foissac, Sarah Djebali, et al., BMC Biology 2019. DOI: 10.1186/s12915-019-0726-5

Thrombolysis During Resuscitation for Out-of-Hospital Cardiac Arrest Caused by Pulmonary Embolism Increases 30-Day Survival. François Javaudin, Jean-Baptiste Lascarrou, ..., Chloé Latour, et al., Chest 2019. DOI: 10.1016/j.chest.2019.07.015

A receptor-like kinase enhances sunflower resistance to Orobanche cumana. Pauline Duriez, Sonia Vautrin, ..., Stéphane Muños, Nature Plants 2019. DOI: 10.1038/s41477-019-0556-z

Associated anomalies in cases with agenesis of the corpus callosum. Claude Stoll, Béatrice Dott, Marie‐Paule Roth, American Journal of Medical Genetics Part A 2019. DOI: 10.1002/ajmg.a.61330

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome. Sabrina Bondu, Anne‐Sophie Alary, ..., Léon Kautz, et al., Science Translational Medicine 2019. DOI: 10.1126/scitranslmed.aav5467

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. Clémence Massip, Priscilla Branchu, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2019. DOI: 10.1371/journal.ppat.1008029

SGI-4 in Monophasic Salmonella Typhimurium ST34 Is a Novel ICE That Enhances Resistance to Copper. Priscilla Branchu, Oliver J. Charity, et al., Frontiers in Microbiology 2019. DOI: 10.3389/fmicb.2019.01118

Vegan diet in children and adolescents. Recommendations from the French-speaking Pediatric Hepatology, Gastroenterology and Nutrition Group (GFHGNP). Julie Lemale, Emmanuel Mas, et al., Archives de Pédiatrie 2019. DOI: 10.1016/j.arcped.2019.09.001

Emergence of methicillin-resistant Staphylococcus aureus (MRSA) ST8 in raw milk and traditional dairy products in the Tizi Ouzou area of Algeria. Yacine Titouche, Ahcène Hakem, ..., Frédéric Auvray, Journal of Dairy Science 2019. DOI: 10.3168/jds.2018-16208

Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization. Peter T. McKenney, Jinyuan Yan, Julien Vaubourgeix, et al., Cell Host & Microbe 2019. DOI: 10.1016/j.chom.2019.03.008

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Alberto Caminero, Justin L. McCarville, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Nature Communications 2019. DOI: 10.1038/s41467-019-09037-9

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner. Marion Rincel, P. Aubert, ..., Nathalie Vergnolle, et al., Brain, Behavior, and Immunity 2019. DOI: 10.1016/j.bbi.2019.03.006

House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation. Nadine Serhan, Lilian Basso, ..., Chrystelle Bonnart, et al., Nature Immunology 2019. DOI: 10.1038/s41590-019-0493-z

Pathobiont release from dysbiotic gut microbiota biofilms in intestinal inflammatory diseases: a role for iron?. André G. Buret, Jean‐Paul Motta, et al., Journal of Biomedical Science 2019. DOI: 10.1186/s12929-018-0495-4

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Alvaro Barbeira, Scott Dickinson, ..., Jean Monlong, et al., Nature Communications 2018. DOI: 10.1038/s41467-018-03621-1

Global characterization of copy number variants in epilepsy patients from whole genome sequencing. Jean Monlong, Simon Girard, et al., PLOS Genetics 2018. DOI: 10.1371/journal.pgen.1007285

Human copy number variants are enriched in regions of low mappability. Jean Monlong, Patrick Cossette, et al., Nucleic Acids Research 2018. DOI: 10.1093/nar/gky538

Whole-genome landscape of Medicago truncatula symbiotic genes. Yann Pécrix, S. Evan Staton, ..., Stéphane Muños, et al., Nature Plants 2018. DOI: 10.1038/s41477-018-0286-7

Sunflower pan-genome analysis shows that hybridization altered gene content and disease resistance. Sariel Hübner, Natalia Bercovich, ..., Stéphane Muños, et al., Nature Plants 2018. DOI: 10.1038/s41477-018-0329-0

Ten Broad Spectrum Resistances to Downy Mildew Physically Mapped on the Sunflower Genome. Yann Pécrix, Charlotte Penouilh-Suzette, Stéphane Muños, et al., Frontiers in Plant Science 2018. DOI: 10.3389/fpls.2018.01780

Shift in skin microbiota of Western European women across aging. Romain Jugé, Pauline Rouaud, ..., Marie‐Paule Roth, Hélène Coppin, et al., Journal of Applied Microbiology 2018. DOI: 10.1111/jam.13929

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. Nadège Bossuet‐Greif, Julien Vignard, Frédéric Taïeb, ..., Éric Oswald, Jean‐Philippe Nougayrède, mBio 2018. DOI: 10.1128/mbio.02393-17

Genome Variation and Molecular Epidemiology of Salmonella enterica Serovar Typhimurium Pathovariants. Priscilla Branchu, Matt Bawn, et al., Infection and Immunity 2018. DOI: 10.1128/iai.00079-18

NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis. Audrey Ferrand, Ziad Al Nabhani, ..., Emmanuel Mas, ..., Frédérick Barreau, Cellular and Molecular Gastroenterology and Hepatology 2018. DOI: 10.1016/j.jcmgh.2018.10.009

Management of Juvenile Polyposis Syndrome in Children and Adolescents. Shlomi Cohen, Warren Hyer, Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2018. DOI: 10.1097/mpg.0000000000002246

Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study. Fabienne Charbit‐Henrion, Marianna Parlato, ..., Emmanuel Mas, et al., Journal of Crohn's and Colitis 2018. DOI: 10.1093/ecco-jcc/jjy068

Targeting the Proteostasis Network for Mycobacterial Drug Discovery. Tania J. Lupoli, Julien Vaubourgeix, et al., ACS Infectious Diseases 2018. DOI: 10.1021/acsinfecdis.7b00231

Neurons and Glia in the Enteric Nervous System and Epithelial Barrier Function. Nathalie Vergnolle, Carla Cirillo, Physiology 2018. DOI: 10.1152/physiol.00009.2018

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Julien Bricambert, Marie‐Clotilde Alves‐Guerra, ..., François Canonne‐Hergaux, et al., Nature Communications 2018. DOI: 10.1038/s41467-018-04361-y

An atlas of human long non-coding RNAs with accurate 5′ ends. Chung-Chau Hon, Jordan A. Ramilowski, ..., Sarah Djebali, et al., Nature 2017. DOI: 10.1038/nature21374

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge. Chloé Latour, Céline Besson‐Fournier, ..., Delphine Meynard, Marie‐Paule Roth, Hélène Coppin, Blood 2017. DOI: 10.1182/blood-2017-07-795658

The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution. Hélène Badouin, Jérôme Gouzy, ..., Stéphane Muños, et al., Nature 2017. DOI: 10.1038/nature22380

Potential impact of the herbicide 2,4-dichlorophenoxyacetic acid on human and ecosystems. Faisal Islam, Jian Wang, ..., Stéphane Muños, et al., Environment International 2017. DOI: 10.1016/j.envint.2017.10.020

Genetic control of plasticity of oil yield for combined abiotic stresses using a joint approach of crop modelling and genome‐wide association. Brigitte Mangin, Pierre Casadebaig, ..., Stéphane Muños, et al., Plant, Cell & Environment 2017. DOI: 10.1111/pce.12961

The genetics underlying natural variation of plant–plant interactions, a beloved but forgotten member of the family of biotic interactions. Harihar Jaishree Subrahmaniam, Cyril Libourel, ..., Stéphane Muños, et al., The Plant Journal 2017. DOI: 10.1111/tpj.13799

Associated anomalies in cases with esophageal atresia. Claude Stoll, Yves Alembik, ..., Marie‐Paule Roth, American Journal of Medical Genetics Part A 2017. DOI: 10.1002/ajmg.a.38303

Immunoassay for human serum erythroferrone. Tomas Ganz, Grace Jung, ..., Léon Kautz, et al., Blood 2017. DOI: 10.1182/blood-2017-04-777987

Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis. Sarah Tomkovich, Ye Yang, ..., Éric Oswald, et al., Cancer Research 2017. DOI: 10.1158/0008-5472.can-16-3472

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917. Teresa Pérez, Julien Pujo, ..., Frédérick Barreau, ..., Éric Oswald, et al., Nature Communications 2017. DOI: 10.1038/s41467-017-01403-9

The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. Delphine Payros, Ulrich Dobrindt, ..., Éric Oswald, et al., mBio 2017. DOI: 10.1128/mbio.00007-17

Nod2: The intestinal gate keeper. Ziad Al Nabhani, Gilles Dietrich, ..., Frédérick Barreau, PLOS Pathogens 2017. DOI: 10.1371/journal.ppat.1006177

Continuousin vitroexposure of intestinal epithelial cells to E171 food additive causes oxidative stress, inducing oxidation of DNA bases but no endoplasmic reticulum stress. Marie Dorier, David Béal, ..., Frédérick Barreau, et al., Nanotoxicology 2017. DOI: 10.1080/17435390.2017.1349203

Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis. Hélène Botella, Guangli Yang, ..., Julien Vaubourgeix, mBio 2017. DOI: 10.1128/mbio.01183-17

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Laure Botella, Julien Vaubourgeix, et al., Nature Communications 2017. DOI: 10.1038/ncomms14731

Protectin D1_{n-3 DPA} and resolvin D5_{n-3 DPA} are effectors of intestinal protection. Thomas Gobbetti, Jesmond Dalli, ..., Nathalie Vergnolle, Céline Deraison, et al., Proceedings of the National Academy of Sciences 2017. DOI: 10.1073/pnas.1617290114

Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Claire Rolland-Fourcade, Alexandre Denadai‐Souza, ..., Jean‐Paul Motta, ..., Céline Deraison, Nathalie Vergnolle, Gut 2017. DOI: 10.1136/gutjnl-2016-312094

Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms. Jennifer Beatty, Sarah Akierman, Jean‐Paul Motta, et al., International Journal for Parasitology 2017. DOI: 10.1016/j.ijpara.2016.11.010

Hydrogen sulfide: an agent of stability at the microbiome-mucosa interface. John L. Wallace, Jean‐Paul Motta, et al., American Journal of Physiology-Gastrointestinal and Liver Physiology 2017. DOI: 10.1152/ajpgi.00249.2017

Interactions of*Giardia sp.*with the intestinal barrier: Epithelium, mucus, and microbiota. Thibault Allain, Christina Amat, Jean‐Paul Motta, et al., Tissue Barriers 2017. DOI: 10.1080/21688370.2016.1274354

Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease. Anna Mańko, Jean‐Paul Motta, et al., PLOS ONE 2017. DOI: 10.1371/journal.pone.0178647

Cysteine Protease–Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection. Christina Amat, Jean‐Paul Motta, et al., The American Journal of Pathology 2017. DOI: 10.1016/j.ajpath.2017.07.009

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism. Thomas Farge, Estelle Saland, ..., Stéphanie Cassant‐Sourdy, et al., Cancer Discovery 2017. DOI: 10.1158/2159-8290.cd-16-0441

A benchmark for RNA-seq quantification pipelines. Mingxiang Teng, Michael I. Love, ..., Sarah Djebali, et al., Genome Biology 2016. DOI: 10.1186/s13059-016-0940-1

Gene-specific patterns of expression variation across organs and species. Alessandra Breschi, Sarah Djebali, et al., Genome Biology 2016. DOI: 10.1186/s13059-016-1008-y

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice. Antonella Nai, Aude Rubio, ..., Chloé Latour, Céline Besson‐Fournier, ..., Hélène Coppin, ..., Delphine Meynard, Blood 2016. DOI: 10.1182/blood-2015-11-681494

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B. Céline Besson‐Fournier, Aurélie Gineste, Chloé Latour, ..., Delphine Meynard, ..., Éric Oswald, Hélène Coppin, Marie‐Paule Roth, Blood 2016. DOI: 10.1182/blood-2016-10-748541

Extraction of High-Molecular-Weight Genomic DNA for Long-Read Sequencing of Single Molecules. Baptiste Mayjonade, Jérôme Gouzy, ..., Stéphane Muños, BioTechniques 2016. DOI: 10.2144/000114460

Sunflower Resistance to Broomrape (Orobanche cumana) Is Controlled by Specific QTLs for Different Parasitism Stages. Johann Louarn, Marie‐Claude Boniface, ..., Stéphane Muños, Frontiers in Plant Science 2016. DOI: 10.3389/fpls.2016.00590

RXLR and CRN Effectors from the Sunflower Downy Mildew Pathogen Plasmopara halstedii Induce Hypersensitive-Like Responses in Resistant Sunflower Lines. Quentin Gascuel, Luis Buendia, ..., Stéphane Muños, et al., Frontiers in Plant Science 2016. DOI: 10.3389/fpls.2016.01887

Decreased Bone Formation Explains Osteoporosis in a Genetic Mouse Model of Hemochromatosiss. Mathilde Doyard, Daniel Chappard, ..., Marie‐Paule Roth, et al., PLOS ONE 2016. DOI: 10.1371/journal.pone.0148292

The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin. Frédéric Taïeb, C. Petit, Jean‐Philippe Nougayrède, Éric Oswald, EcoSal Plus 2016. DOI: 10.1128/ecosalplus.esp-0008-2016

MATE transport of the E. coli-derived genotoxin colibactin. Jarrod J. Mousa, Ye Yang, ..., Éric Oswald, et al., Nature Microbiology 2016. DOI: 10.1038/nmicrobiol.2015.9

Early settlers: whichE. colistrains do you not want at birth?. Thomas Sécher, Camille Bréhin, Éric Oswald, American Journal of Physiology-Gastrointestinal and Liver Physiology 2016. DOI: 10.1152/ajpgi.00091.2016

Microevolution of Monophasic Salmonella Typhimurium during Epidemic, United Kingdom, 2005–2010. Liljana Petrovska, Alison E. Mather, ..., Priscilla Branchu, et al., Emerging Infectious Diseases 2016. DOI: 10.3201/eid2204.150531

Nod2Deficiency Leads to a Specific and Transmissible Mucosa-associated Microbial Dysbiosis Which Is Independent of the Mucosal Barrier Defect. Ziad Al Nabhani, Patricia Lepage, ..., Frédérick Barreau, Journal of Crohn's and Colitis 2016. DOI: 10.1093/ecco-jcc/jjw095

The Intestinal Microenvironment and Functional Gastrointestinal Disorders. Giovanni Barbara, Christine Feinle‐Bisset, ..., Nathalie Vergnolle, et al., Gastroenterology 2016. DOI: 10.1053/j.gastro.2016.02.028

Protease inhibition as new therapeutic strategy for GI diseases. Nathalie Vergnolle, Gut 2016. DOI: 10.1136/gutjnl-2015-309147

Giardia duodenalisinduces paracellular bacterial translocation and causes postinfectious visceral hypersensitivity. Marie C. M. Halliez, Jean‐Paul Motta, et al., American Journal of Physiology-Gastrointestinal and Liver Physiology 2016. DOI: 10.1152/ajpgi.00144.2015